Developmental FunctionaL Annotation at Tufts


The pathway not taken: understanding ‘omics data in the perinatal context . Edlow AG, Slonim DK, Wick HC, Hui L, Bianchi DW. American Journal of Obstetrics and Gynecology, 213(1): 59. 2015.

DFLAT: Functional Annotation for Human Development . Wick HC, Drabkin H, Ngu H, Sackman M, Fournier C, Haggett J, Blake JA, Bianchi DW, Slonim DK. BMC Bioinformatics, 15(1): 45. 2014.

Maternal Obesity Affects Fetal Neurodevelopmental and Metabolic Gene Expression: A Pilot Study . Edlow AG, Vora NL, Hui L, Wick HC, Cowan JM, Bianchi DW. PLoS ONE, 9(2): e88661. 2014.

Global gene expression analysis of term amniotic fluid cell-free fetal RNA . Hui L, Wick HC, Edlow AG, Cowan JM, Bianchi DW. Obstet Gynecol, 121(6): 1248-1254. 2013.

Global gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome . Hui L, Wick HC, Moise KJ Jr, Johnson A, Luks F, Haeri S, Johnson KL, Bianchi DW. Prenat Diagn, 33(9): 873-883. 2013

Age matters: functional annotation tailored to human development improves our understanding of fetal transcriptional profiles . Heather Wick, David P. Hill, Judith A. Blake, Huy Ngu, Michael Sackman, Craig Fournier, Diana W. Bianchi, Donna K. Slonim. International Conference on Intelligent Systems for Molecular Biology and European Conference on Computational Biology, Jul. 2011.

Mining functionally relevant gene sets for analyzing physiologically novel clinical expression data . Sevin Turcan, Doug E. Vetter, Jill L. Maron, Xintao Wei, and Donna K. Slonim. Pacific Symposium on Biocomputing, Jan. 2011.

Transcriptomic analysis of cell-free fetal RNA suggests a specific molecular phenotype in trisomy 18 . Koide K, Slonim DK, Johnson KL, Tantravahi U, Cowan JM, Bianchi DW. Hum Genet., 129(3):295-305, Mar. 2011.

Lack of nAChR Activity Depresses Cochlear Maturation and Up-Regulates GABA System Components: Temporal Profiling of Gene Expression in a9 Null Mice . Sevin Turcan, Donna K. Slonim, and Doug E. Vetter. PLoS One, 5(2):e9058, Feb. 2010.

Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses . Donna K. Slonim*, Keiko Koide*, Kirby L. Johnson, Umadevi Tantravahi, Janet M. Cowan, Zina Jarrah, Diana W. Bianchi. Proceedings of the National Academy of Sciences USA, 106(23):9425-9, June, 2009.

Gene expression analysis in pregnant women and their infants identifies unique fetal biomarkers that circulate in maternal blood . Jill L. Maron, Kirby L. Johnson, Donna Slonim, Chao-Qiang Lai, Marco Ramoni, Gil Alterovitz, Zina Jarrah, Zinger Yang, and Diana W. Bianchi. Journal of Clinical Investigation, 117(10):3007-19, Oct., 2007.